Varley, R;
Cowell, PE;
Dyson, L;
Inglis, L;
Roper, A;
Whiteside, SP;
(2016)
Self-Administered Computer Therapy for Apraxia of Speech: Two-Period Randomized Control Trial With Crossover.
Stroke
, 47
(3)
pp. 822-828.
10.1161/STROKEAHA.115.011939.
Preview |
Text
Varley_et al_Stroke_accepted.pdf Download (606kB) | Preview |
Abstract
BACKGROUND AND PURPOSE: There is currently little evidence on effective interventions for poststroke apraxia of speech. We report outcomes of a trial of self-administered computer therapy for apraxia of speech. / METHODS: Effects of speech intervention on naming and repetition of treated and untreated words were compared with those of a visuospatial sham program. The study used a parallel-group, 2-period, crossover design, with participants receiving 2 interventions. Fifty participants with chronic and stable apraxia of speech were randomly allocated to 1 of 2 order conditions: speech-first condition versus sham-first condition. Period 1 design was equivalent to a randomized controlled trial. We report results for this period and profile the effect of the period 2 crossover. / RESULTS: Period 1 results revealed significant improvement in naming and repetition only in the speech-first group. The sham-first group displayed improvement in speech production after speech intervention in period 2. Significant improvement of treated words was found in both naming and repetition, with little generalization to structurally similar and dissimilar untreated words. Speech gains were largely maintained after withdrawal of intervention. There was a significant relationship between treatment dose and response. However, average self-administered dose was modest for both groups. Future software design would benefit from incorporation of social and gaming components to boost motivation. / CONCLUSIONS: Single-word production can be improved in chronic apraxia of speech with behavioral intervention. Self-administered computerized therapy is a promising method for delivering high-intensity speech/language rehabilitation. CLINICAL TRIAL REGISTRATION: URL: http://orcid.org/0000-0002-1278-0601. Unique identifier: ISRCTN88245643.
| Type: | Article |
|---|---|
| Title: | Self-Administered Computer Therapy for Apraxia of Speech: Two-Period Randomized Control Trial With Crossover |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1161/STROKEAHA.115.011939 |
| Publisher version: | http://dx.doi.org/10.1161/STROKEAHA.115.011939 |
| Language: | English |
| Additional information: | Copyright © 2016 American Heart Association, Inc. The published version of record is available on the journal website at http://dx.doi.org/10.1161/STROKEAHA.115.011939 |
| Keywords: | Aphasia, apraxias, computers, cross-over studies, speech, therapeutics |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Language and Cognition |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1474408 |
Archive Staff Only
 |
View Item |
