Loh, XJ;
Lee, T-C;
Dou, Q;
Deen, GR;
(2016)
Utilising inorganic nanocarriers for gene delivery.
Biomaterials Science
, 4
(1)
pp. 70-86.
10.1039/C5BM00277J.
Preview |
Text
Gene_delivery_by_NPs_(accepted version for archive).pdf - Accepted Version Download (1MB) | Preview |
Abstract
The delivery of genetic materials into cells to elicit cellular responses has been extensively studied by biomaterials scientists globally. Many materials such as lipids, peptides, viruses, synthetically modified cationic polymers and certain inorganic nanomaterials could be used to complex the negatively charged plasmids and deliver the formed package into cells. The recent literature on the delivery of genetic materials utilising inorganic nanoparticles is carefully examined in this review. We have picked out the most relevant references and concisely summarised the findings with illustrated examples. We further propose alternative approaches and suggest future pathways towards the practical use of multifunctional nanocarriers.
| Type: | Article |
|---|---|
| Title: | Utilising inorganic nanocarriers for gene delivery |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/C5BM00277J |
| Publisher version: | http://dx.doi.org/10.1039/C5BM00277J |
| Language: | English |
| Additional information: | © Royal Society of Chemistry 2016 |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office > Institute for Materials Discovery |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1474026 |
Archive Staff Only
 |
View Item |
