Parkin, E;
O'Reilly, DA;
Plumb, AA;
Manoharan, P;
Rao, M;
Coe, P;
Frystyk, J;
... Renehan, AG; + view all
(2015)
Digital histology quantification of intra-hepatic fat in patients undergoing liver resection.
European Journal of Surgical Oncology
, 41
(8)
pp. 1020-1027.
10.1016/j.ejso.2015.05.003.
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Abstract
High intra-hepatic fat (IHF) content is associated with insulin resistance, visceral adiposity, and increased morbidity and mortality following liver resection. However, in clinical practice, IHF is assessed indirectly by pre-operative imaging [for example, chemical-shift magnetic resonance (CS-MR)]. We used the opportunity in patients undergoing liver resection to quantify IHF by digital histology (D-IHF) and relate this to CT-derived anthropometrics, insulin-related serum biomarkers, and IHF estimated by CS-MR.
| Type: | Article |
|---|---|
| Title: | Digital histology quantification of intra-hepatic fat in patients undergoing liver resection |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ejso.2015.05.003 |
| Publisher version: | http://dx.doi.org/10.1016/j.ejso.2015.05.003 |
| Language: | English |
| Additional information: | Copyright Elsevier 2015. This article is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0. Access may be initially restricted by the publisher. |
| Keywords: | Hepatic steatosis, Insulin resistance, Liver surgery, Obesity, Visceral adiposity |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1468984 |
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