Guardiola, M;
Exeter, HJ;
Perret, C;
Folkersen, L;
Van't Hooft, F;
Eriksson, P;
Franco-Cereceda, A;
... Talmud, PJ; + view all
(2015)
PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk.
Circ Cardiovasc Genet
, 8
(2)
356 - 362.
10.1161/CIRCGENETICS.114.000633.
Preview |
Text
Cooper_Circ_Cardiovasc_Genet-2015-Guardiola-CIRCGENETICS_114_000633_(4).pdf Download (1MB) | Preview |
Abstract
Observational studies report that secretory phospholipase A2 (sPLA2) activity is a marker for coronary heart disease (CHD) risk, and activity measures are thought to represent the composite activity of sPLA2-IIA, -V, and -X. The aim of this study was to use genetic variants of PLA2G10, encoding sPLA2-X, to investigate the contribution of sPLA2-X to the measure of sPLA2 activity and coronary heart disease (CHD) risk traits and outcome.
Type: | Article |
---|---|
Title: | PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk. |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1161/CIRCGENETICS.114.000633 |
Publisher version: | http://dx.doi.org/10.1161/CIRCGENETICS.114.000633 |
Language: | English |
Additional information: | © 2015 American Heart Association, Inc. |
Keywords: | PLA2G10, genetic polymorphism |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
URI: | https://discovery.ucl.ac.uk/id/eprint/1461268 |
Archive Staff Only
![]() |
View Item |