Lewis, TE;
Sillitoe, I;
Andreeva, A;
Blundell, TL;
Buchan, DW;
Chothia, C;
Cozzetto, D;
... Orengo, C; + view all
(2014)
Genome3D: exploiting structure to help users understand their sequences.
Nucleic Acids Research
, 43
(D1)
D382-D386.
10.1093/nar/gku973.
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Abstract
Genome3D (http://www.genome3d.eu) is a collaborative resource that provides predicted domain annotations and structural models for key sequences. Since introducing Genome3D in a previous NAR paper, we have substantially extended and improved the resource. We have annotated representatives from Pfam families to improve coverage of diverse sequences and added a fast sequence search to the website to allow users to find Genome3D-annotated sequences similar to their own. We have improved and extended the Genome3D data, enlarging the source data set from three model organisms to 10, and adding VIVACE, a resource new to Genome3D. We have analysed and updated Genome3D's SCOP/CATH mapping. Finally, we have improved the superposition tools, which now give users a more powerful interface for investigating similarities and differences between structural models.
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