TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia.

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TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia.

Maschietto, M; Williams, RD; Chagtai, T; Popov, SD; Sebire, NJ; Vujanic, G; Perlman, E; ... Pritchard-Jones, K; + view all (2014) TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia. PLoS One , 9 (10) , Article e109924 . 10.1371/journal.pone.0109924. Green open access

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Abstract

The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers additional prognostic information.

Type:	Article
Title:	TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia.
Location:	United States
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1371/journal.pone.0109924
Publisher version:	http://dx.doi.org/10.1371/journal.pone.0109924
Language:	English
Additional information:	© 2014 Maschietto et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI:	https://discovery.ucl.ac.uk/id/eprint/1451919

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