Isham, L; (2006) Quality of life in paediatric brain cancer. Doctoral thesis , UCL (University College London).

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Abstract

This paper reviews the recent literature on quality of life (QOL) in survivors of paediatric brain tumours. QOL is defined as comprising three domains (physical, emotional and social), and studies investigating single or multiple domains are included. A psychological perspective is taken on QOL whereby it is the degree to which circumstances relating to these domains are distressing or problematic for the individual that is considered key, rather than the circumstances themselves. A total of 23 studies are reviewed and findings are presented in terms of overall QOL, physical QOL, emotional QOL and social QOL. Overall, paediatric brain-tumour survivors appear to be at risk of reduced QOL both when compared to population norms and to other paediatric cancer-populations. Possible risk factors are discussed but fiirther research is needed before definitive conclusions can be reached. Methodological limitations observed in the literature are considered and directions for future research are proposed. In particular, the need for more theory-driven studies is highlighted.

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