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Spatial sensitivity and penetration depth of three cerebral oxygenation monitors

Gunadi, Sonny; Leung, Terence S; Elwell, Clare E; Tachtsidis, Ilias; (2014) Spatial sensitivity and penetration depth of three cerebral oxygenation monitors. Biomedical Optics Express , 5 (9) pp. 2896-2912. 10.1364/BOE.5.002896. Green open access

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Abstract

The spatial sensitivities of NIRO-100, ISS Oximeter and TRS-20 cerebral oxygenation monitors are mapped using the local perturbation method to inform on their penetration depths and susceptibilities to superficial contaminations. The results show that TRS-20 has the deepest mean penetration depth and is less sensitive than the other monitors to a localized absorption change in the superficial layer. However, an integration time of more than five seconds is required by the TRS-20 to achieve an acceptable level of signal-to-noise ratio, which is the poorest amongst the monitors. With the exception of NIRO-100 continuous wave method, the monitors are not significantly responsive to layer-wide absorption change that occurs in the superficial layer.

Type: Article
Title: Spatial sensitivity and penetration depth of three cerebral oxygenation monitors
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/BOE.5.002896
Publisher version: https://doi.org/10.1364/BOE.5.002896
Language: English
Additional information: © 2014 Optical Society of America All articles published under our OAPA are freely accessible, while copyright is transferred to Optica Publishing Group. Authors may post the published version of their article to their personal website, institutional repository, or a repository required by their funding agency. Authors and readers may use, reuse, and build upon the article, or use it for text or data mining, as long as the purpose is non-commercial and appropriate attribution is maintained.
Keywords: (170.0170) Medical optics and biotechnology, (170.3660) Light propagation in tissues, (170.3890) Medical optics instrumentation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1443511
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