Woollacott, IO;
Fletcher, PD;
Massey, LA;
Pasupathy, A;
Rossor, MN;
Caine, D;
Rohrer, JD;
(2015)
Compulsive versifying after treatment of transient epileptic amnesia.
Neurocase
, 21
(5)
pp. 548-553.
10.1080/13554794.2014.953178.
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Abstract
Compulsive production of verse is an unusual form of hypergraphia that has been reported mainly in patients with right temporal lobe seizures. We present a patient with transient epileptic amnesia and a left temporal seizure focus, who developed isolated compulsive versifying, producing multiple rhyming poems, following seizure cessation induced by lamotrigine. Functional neuroimaging studies in the healthy brain implicate left frontotemporal areas in generating novel verbal output and rhyme, while dysregulation of neocortical and limbic regions occurs in temporal lobe epilepsy. This case complements previous observations of emergence of altered behavior with reduced seizure frequency in patients with temporal lobe epilepsy. Such cases suggest that reduced seizure frequency has the potential not only to stabilize or improve memory function, but also to trigger complex, specific behavioral alterations.
| Type: | Article |
|---|---|
| Title: | Compulsive versifying after treatment of transient epileptic amnesia |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/13554794.2014.953178 |
| Publisher version: | http://dx.doi.org/10.1080/13554794.2014.953178 |
| Language: | English |
| Additional information: | © 2014 The Author(s). Published by Taylor & Francis. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
| Keywords: | Dementia, hypergraphia, lamotrigine, poetry, temporal lobe, transient epileptic amnesia, verbal creativity |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1443462 |
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