Gupta, RK;
Marks, M;
Edwards, SG;
Smith, K;
Fletcher, K;
Lee, SM;
Ramsay, A;
... Miller, RF; + view all
(2014)
A declining CD4 count and diagnosis of HIV-associated hodgkin Lymphoma: Do prior clinical symptoms and laboratory abnormalities aid diagnosis?
PLoS One
, 9
(2)
, Article e87442. 10.1371/journal.pone.0087442.
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Abstract
The incidence of Hodgkin lymphoma (HL) among HIV-infected individuals remains unchanged since the introduction of combination antiretroviral therapy (cART). Recent epidemiological data suggest that CD4 count decline over a year is associated with subsequent diagnosis of HL. In an era of economic austerity monitoring the efficacy of cART by CD4 counts may no longer be required where CD4 count>350 cells/µl and viral load is suppressed (<50 copies/ml).
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