Sethi, V; Muhlert, N; Ron, M; Golay, X; Wheeler-Kingshott, CA; Miller, DH; Chard, DT; Sethi, V; Muhlert, N; Ron, M; Golay, X; Wheeler-Kingshott, CA; Miller, DH; Chard, DT; Yousry, TA; - view fewer (2013) MS Cortical Lesions on DIR: Not Quite What They Seem? PLoS One , 8 (11) , Article e78879. 10.1371/journal.pone.0078879.

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Abstract

Accurate identification and localization of cortical gray matter (CGM) lesions in MS is important when determining their clinical relevance. Double inversion recovery (DIR) scans have been widely used to detect MS CGM lesions. Phase sensitive inversion recovery (PSIR) scans have a higher signal to noise, and can therefore be obtained at a higher resolution within clinically acceptable times. This enables detection of more CGM lesions depicting a clearer cortical and juxtacortical anatomy. In this study, we systematically investigated if the use of high resolution PSIR scans changes the classification of CGM lesions, when compared with standard resolution DIR scans.

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