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Chick stem cells: Current progress and future prospects.

Intarapat, S; Stern, CD; (2013) Chick stem cells: Current progress and future prospects. Stem Cell Res , 11 (3) 1378 - 1392. 10.1016/j.scr.2013.09.005. Green open access

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Abstract

Chick embryonic stem cells (cESCs) can be derived from cells obtained from stage X embryos (blastoderm stage); these have the ability to contribute to all somatic lineages in chimaeras, but not to the germ line. However, lines of stem cells that are able to contribute to the germ line can be established from chick primordial germ cells (cPGCs) and embryonic germ cells (cEGCs). This review provides information on avian stem cells, emphasizing different sources of cells and current methods for derivation and culture of pluripotent cells from chick embryos. We also review technologies for isolation and derivation of chicken germ cells and the production of transgenic birds.

Type: Article
Title: Chick stem cells: Current progress and future prospects.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.scr.2013.09.005
Publisher version: http://dx.doi.org/10.1016/j.scr.2013.09.005
Additional information: © 2013 Elsevier B.V. All rights reserved. This work is licensed under a Creative Commons Attribution 3.0 Unported License.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/1410761
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