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The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population

Sheng, X; Murphy, MJ; MacDonald, TM; Wei, L; (2012) The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population. BMC Public Health , 12 , Article 712. 10.1186/1471-2458-12-712. Green open access

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Abstract

Total cholesterol (TC) concentration is the most commonly used measure of statin efficacy in the UK. This study aimed to evaluate the effectiveness of statins in lowering TC, cardiovascular events (CV) and mortality five common chronic diseases (chronic obstructive pulmonary disease (COPD), osteoarthritis (OA), rheumatoid arthritis (RA), chronic kidney disease (CKD), and diabetes mellitus (DM)) and to compare effectiveness with the rest of the population not recorded as having these diseases.

Type: Article
Title: The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1471-2458-12-712
Publisher version: http://dx.doi.org/10.1186/1471-2458-12-712
Language: English
Additional information: © 2012 Sheng et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC3490740
Keywords: Aged, Aged, 80 and over, Arthritis, Rheumatoid, Cardiovascular Diseases, Chronic Disease, Cohort Studies, Comparative Effectiveness Research, Female, Great Britain, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypercholesterolemia, Male, Middle Aged, Osteoarthritis, Outcome Assessment (Health Care), Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency, Chronic
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Practice and Policy
URI: https://discovery.ucl.ac.uk/id/eprint/1387173
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