Theveneau, E;
Mayor, R;
(2012)
Cadherins in collective cell migration of mesenchymal cells.
Current Opinion in Cell Biology
, 24
(5)
677 - 684.
10.1016/j.ceb.2012.08.002.
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Abstract
Immunity, embryogenesis and tissue repair rely heavily on cell migration. Cells can be seen migrating as individuals or large groups. In the latter case, collectiveness emerges via cell-cell interactions. In migratory epithelial cell sheets, classic Cadherins are critical to maintain tissue integrity, to promote coordination and establish cell polarity. However, recent evidence indicates that mesenchymal cells, migrating in streams such as neural crest or cancer cells, also exhibit collective migration. Here we will explore the idea that Cadherins play an essential role during collective migration of mesenchymal cells.
| Type: | Article |
|---|---|
| Title: | Cadherins in collective cell migration of mesenchymal cells |
| Location: | UK |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ceb.2012.08.002 |
| Publisher version: | http://dx.doi.org/10.1016/j.ceb.2012.08.002 |
| Language: | English |
| Keywords: | Animals, Cadherins, Cell Adhesion, Cell Movement, Cell Polarity, Mesoderm, Neural Crest |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1377560 |
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