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Botulinum toxin type A in the treatment of hemifacial spasm: An 11-year experience

Barbosa, ER; Takada, LT; Goncalves, LR; Costa, RMPD; Silveira-Moriyama, L; Chien, HF; (2010) Botulinum toxin type A in the treatment of hemifacial spasm: An 11-year experience. ARQ NEURO-PSIQUIAT , 68 (4) 502 - 505. 10.1590/S0004-282X2010000400006. Green open access

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Abstract

In order to evaluate the long-term effect of botulinum toxin type A (BTX) in the treatment of hemifacial spasm (HFS), a retrospective analysis of patients treated at the Movement Disorders Unit of the Division of Neurology, Clinical Hospital, University of Sao Paulo, School of Medicine from 1993 to 2004 was made. A total of 808 injections with BTX were administered to 54 patients with HFS. The mean duration of improvement per application was 3.46 months and the mean rate of improvement using subjective judgement by the patient was of 83%. Adverse effects, mostly minor, were observed in 64.8% of patients at least once along the period of follow-up and the most frequent of them was orbicularis oris paralysis (38.8%). There was no decrement in response when compared the first and the last injection recorded.

Type: Article
Title: Botulinum toxin type A in the treatment of hemifacial spasm: An 11-year experience
Open access status: An open access version is available from UCL Discovery
DOI: 10.1590/S0004-282X2010000400006
Publisher version: http://dx.doi.org/10.1590/S0004-282X2010000400006
Language: English
Additional information: All the contents of www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
Keywords: botulinum toxin, hemifacial spasm, BLEPHAROSPASM, EFFICACY
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/134991
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