Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation.

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Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation.

Ioannoni, R; Beaudoin, J; Lopez-Maury, L; Codlin, S; Bahler, J; Labbe, S; (2012) Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation. PLoS One , 7 (4) , Article e36338. 10.1371/journal.pone.0036338. Green open access

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Abstract

Meiosis is the specialized form of the cell cycle by which diploid cells produce the haploid gametes required for sexual reproduction. Initiation and progression through meiosis requires that the expression of the meiotic genes is precisely controlled so as to provide the correct gene products at the correct times. During meiosis, four temporal gene clusters are either induced or repressed by a cascade of transcription factors.

Type:	Article
Title:	Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation.
Location:	United States
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1371/journal.pone.0036338
Publisher version:	http://dx.doi.org/10.1371/journal.pone.0036338
Language:	English
Additional information:	© 2012 Ioannoni et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3338643 This work was supported in part by grants MOP-3645 and MOP-114986 from the Canadian Institutes of Health Research (CIHR), and by a grant from the Foundation of Stars for Children's Health Research awarded to SL. This study was also supported by a Cancer Research UK grant (CUK C9546/A6517) to JB. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Keywords:	Amino Acid Sequence, Anaphase, Cell Cycle Proteins, Chromosomes, Fungal, Gene Deletion, Gene Expression Regulation, Fungal, Intracellular Space, Meiosis, Metaphase, Molecular Sequence Data, Protein Transport, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Spores, Fungal
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI:	https://discovery.ucl.ac.uk/id/eprint/1346561