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Exon level integration of proteomics and microarray data

Bitton, DA; Okoniewski, MJ; Connolly, Y; Miller, CJ; (2008) Exon level integration of proteomics and microarray data. In: BMC BIOINFORMATICS. (pp. -). BIOMED CENTRAL LTD Green open access

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Abstract

Background:Previous studies investigating the correspondence between mRNA expression level and protein abundance have generally reported low correlation. Complexities in the processes that regulate gene expression are often assumed to be a major cause of inconsistency between the two. We hypothesised that other factors, such as the reliability of the quantification technologies, the relative locations of the reporters with respect to the transcripts and proteins, and the supporting bioinformatics tools, might also contribute to the observed differences.

Type: Proceedings paper
Title: Exon level integration of proteomics and microarray data
Event: 4th International-Society-for-Computational-Biology Student Council Symposium held at the 16th Annual International Conference on Intelligent Systems for Molecular Biology
Location: Toronto, CANADA
Dates: 2008-07-18
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1471-2105-9-S10-P2
Publisher version: http://dx.doi.org/10.1186/1471-2105-9-S10-P2
Language: English
Additional information: from Fourth International Society for Computational Biology (ISCB) Student Council Symposium © 2008 Bitton et al; licensee BioMed Central Ltd
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1325267
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