Bitton, DA;
Okoniewski, MJ;
Connolly, Y;
Miller, CJ;
(2008)
Exon level integration of proteomics and microarray data.
In:
BMC BIOINFORMATICS.
(pp. -).
BIOMED CENTRAL LTD
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Abstract
Background:Previous studies investigating the correspondence between mRNA expression level and protein abundance have generally reported low correlation. Complexities in the processes that regulate gene expression are often assumed to be a major cause of inconsistency between the two. We hypothesised that other factors, such as the reliability of the quantification technologies, the relative locations of the reporters with respect to the transcripts and proteins, and the supporting bioinformatics tools, might also contribute to the observed differences.
Type: | Proceedings paper |
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Title: | Exon level integration of proteomics and microarray data |
Event: | 4th International-Society-for-Computational-Biology Student Council Symposium held at the 16th Annual International Conference on Intelligent Systems for Molecular Biology |
Location: | Toronto, CANADA |
Dates: | 2008-07-18 |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1186/1471-2105-9-S10-P2 |
Publisher version: | http://dx.doi.org/10.1186/1471-2105-9-S10-P2 |
Language: | English |
Additional information: | from Fourth International Society for Computational Biology (ISCB) Student Council Symposium © 2008 Bitton et al; licensee BioMed Central Ltd |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences |
URI: | https://discovery.ucl.ac.uk/id/eprint/1325267 |
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