Grice, S.-J.; (2002) The electrophysiology of face perceptions in Williams Syndrome. Doctoral thesis , University of London.

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Abstract

Williams Syndrome is a rare genetic disorder in which the processing of faces and visual 'perception' has been argued to be intact despite other 'deficits' of visuospatial processing. In contrast, the theoretical approach taken in this thesis argues that the brains of those with developmental disorders cannot be legitimately viewed in terms of sparing and impairment, but must be considered as having atypical properties emergent as a result of atypical development. The event-related potential technique is used to provide evidence of abnormalities of perception of visual stimuli, including faces, even within the first 250ms of processing. A new approach to the brain imaging of people with developmental disorders is discussed. The thesis concludes by proposing an 'abnormal binding' hypothesis which aims to explain the nature and neural basis of the visuo-cognitive processing abnormalities in Williams Syndrome.

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