Vaidya, JS; (2010) The UK Experience. In: Kuerer, HM, (ed.) Kuerer's Breast Surgical Oncology. (pp. 535-555). McGraw-Hill: New York, NY, USA.

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Abstract

The United Kingdom has one of the highest incidences of breast cancer (123 per 100,000 women were diagnosed with breast cancer in 2005) and has historically been home to pioneers of breast cancer treatments. Without being exhaustive, the trials originating in the United Kingdom over the last century have contributed significantly to improving our understanding about breast cancer and changed practice worldwide. Many of these trials have a story behind them that illustrates how conceptual leaps essential for progress in medicine are taken. The current TARGIT (TARGeted Intraoperative radioTherapy) trial is a story that will be highlighted because it demonstrates the interweaving of various new concepts in the evolution of local treatment of breast cancer.

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