McNerney, R;
Mallard, K;
Urassa, HMR;
Lemma, E;
Donoghue, HD;
(2007)
Colorimetric phage-based assay for detection of rifampin-resistant Mycobacterium tuberculosis.
Journal of Clinical Microbiology
, 45
(4)
1330 - 1332.
10.1128/JCM.02028-06.
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Abstract
Tests based on bacteriophage replication enable rapid screening of Mycobacterium tuberculosis for drug resistance. We describe a novel broth-based colorimetric method for detecting phage replication. When clinical isolates were tested by this novel method, high concordance was observed with both the traditional phage assay and gene mutation analysis for detection of resistance to rifampin.
Type: | Article |
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Title: | Colorimetric phage-based assay for detection of rifampin-resistant Mycobacterium tuberculosis |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1128/JCM.02028-06 |
Publisher version: | http://dx.doi.org/10.1128/JCM.02028-06 |
Language: | English |
Additional information: | Originally published by ASM: http://dx.doi.org/10.1128/JCM.02028-06 |
Keywords: | Susceptibility |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity |
URI: | https://discovery.ucl.ac.uk/id/eprint/113970 |
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