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The health effects of vaping and e-cigarettes: consensus recommendations

Kouzoukas, E; Navas, C; Zawertailo, L; Fougere, C; Bacon, SL; Chadi, N; Evans, WK; ... Selby, P; + view all (2026) The health effects of vaping and e-cigarettes: consensus recommendations. International Journal of Drug Policy , 148 , Article 105117. 10.1016/j.drugpo.2025.105117. (In press). Green open access

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Abstract

Objective To develop evidence-informed recommendations on the health effects of e-cigarettes to guide healthcare practitioners and the public to balance individual and population harm reduction. Methods Systematic and umbrella reviews investigating the health effects of e-cigarette use were conducted (September 2017 – January 2024). An international panel of subject matter experts (n = 23) and people in Canada with lived experience (n = 7) participated in a two-day, hybrid meeting, and used a consensus-based approach to develop recommendations. A guidance resource and four accompanying knowledge products were tested for usability with end users. Results Consensus was reached on 14 recommendations spanning four health effects: carcinogen exposure, cardiovascular health, respiratory health, and nicotine dependence. Quality of evidence was voted as ranging from high/moderate to moderate/low, and strength of most recommendations was voted as strong. Conclusions Guidance has been informed by best available evidence and expertise, providing direction to support decision-making. The use of established methods to evaluate divergent published literature combined with consensus-building methods among a range of stakeholders on vaping is possible. As higher quality evidence continues to emerge, recommendations will require iterative refinement.

Type: Article
Title: The health effects of vaping and e-cigarettes: consensus recommendations
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.drugpo.2025.105117
Publisher version: https://doi.org/10.1016/j.drugpo.2025.105117
Language: English
Additional information: © 2025 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Consensus, E-cigarettes, Guidance, Nicotine, Public health, Vapes
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/10219759
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