Hollands, Gareth;
Shemilt, Ian;
Sutcliffe, Katy;
Stansfield, Claire;
Sowden, Amanda;
Thomas, James;
(2025)
Harmful health effects of e-cigarettes (vapes) and other non-tobacco oral nicotine products, trends in their use, and interventions: living protocol for a living evidence map and linked research digests.
F1000Research
, 14
, Article 609. 10.12688/f1000research.165927.1.
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Abstract
There is a recognised need to further understand potential harms from the use of e-cigarettes and other non-tobacco oral nicotine products (ONPs), particularly among children and young people. This protocol describes a programme of work that aims to continually identify and classify the evolving international evidence base on the effects of these products on human health, trends in their use, and related interventions. In terms of its methods, we will produce and maintain a living evidence map, available in an online interactive format, and updated continually over the planned duration of the project (~5 years from registration). A wide range of electronic databases will be searched, with eligible articles including a focus on the use of e-cigarettes or ONPs in humans. Should satisfactory levels of machine performance be reached (by reference to human performance benchmarks), we intend to automate the bulk screening of articles for inclusion using Large Language Model (LLM) decisions. A similar approach will be applied to the automated coding of a range of characteristics of included articles, including their type of research, and the nature of harms and products being examined. In conjunction with the production of the living evidence map, we will produce regular descriptive surveillance reports (research digests) that will summarise the current contents of the map. Ongoing production and maintenance of this living evidence map and linked outputs will enable potential users – including across research, policy, and charitable sectors – to more efficiently establish an overview of the landscape of relevant research and surveil key developments.
| Type: | Article |
|---|---|
| Title: | Harmful health effects of e-cigarettes (vapes) and other non-tobacco oral nicotine products, trends in their use, and interventions: living protocol for a living evidence map and linked research digests |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.12688/f1000research.165927.1 |
| Publisher version: | https://doi.org/10.12688/f1000research.165927.1 |
| Language: | English |
| Additional information: | © 2025 Hollands GJ et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). |
| Keywords: | vaping; vapes; e-cigarettes; oral nicotine products; health; harms; living evidence map; evidence synthesis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Research Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10219234 |
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