Hofmaenner, Daniel A;
Singer, Mervyn;
(2024)
Challenging management dogma where evidence is non-existent, weak, or outdated: part II.
Intensive Care Medicine
, 50
(11)
pp. 1804-1813.
10.1007/s00134-024-07634-x.
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Abstract
Many dogmas influence daily clinical practice, and critical care medicine is no exception. We previously highlighted the weak, questionable, and often contrary evidence base underpinning four established medical managements—loop diuretics for acute heart failure, routine use of heparin thromboprophylaxis, rate of sodium correction for hyponatremia, and ‘every hour counts’ for treating bacterial meningitis. We now provide four further examples in this “Dogma II” piece (a week’s course of antibiotics, diabetic ketoacidosis algorithms, sodium bicarbonate to improve ventricular contractility during severe metabolic acidosis, and phosphate replacement for hypophosphatemia) where routine practice warrants re-appraisal.
| Type: | Article |
|---|---|
| Title: | Challenging management dogma where evidence is non-existent, weak, or outdated: part II |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00134-024-07634-x |
| Publisher version: | http://dx.doi.org/10.1007/s00134-024-07634-x |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Critical Care Medicine, General & Internal Medicine, Dogma, Medical evidence, Antibiotic treatment, Diabetic ketoacidosis, Sodium bicarbonate, Phosphate replacement, CRITICALLY-ILL PATIENTS, COMMUNITY-ACQUIRED PNEUMONIA, BICARBONATE THERAPY, ANTIBIOTIC-TREATMENT, SODIUM-BICARBONATE, INTRACELLULAR PH, DOUBLE-BLIND, INTRAABDOMINAL INFECTION, DIABETIC-KETOACIDOSIS, REFEEDING SYNDROME |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10218724 |
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