Baldomero, Helen;
Neumann, Daniel;
Hamad, Nada;
Atsuta, Yoshiko;
Sureda, Anna;
Iida, Minako;
Karduss, Amado;
... Niederwieser, Dietger; + view all
(2024)
The role of registries in hematological disorders.
Best Practice & Research Clinical Haematology
, 37
(2)
, Article 101556. 10.1016/j.beha.2024.101556.
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Abstract
Hematopoietic cell transplantation (HCT) was developed more than 65 years ago to treat malignant blood disorders and irreversible bone marrow failures, with the aim of replacing a diseased hematopoietic system with a healthy one (allogeneic HCT). Decades later, the procedure was adapted to apply maximal chemotherapy or radiotherapy, which would result in bone marrow failure, but could be remedied by an infusion of a patient's own cryopreserved bone marrow (autologous HCT). Both treatments are high-risk and complex, especially during the initial phases. However, concerted efforts, vision, and collaboration between physicians and centers worldwide have resulted in HCT becoming a standard of care for many hematological disorders with progressive improvements in outcomes. Registries and the collaboration of societies worldwide have enabled the delivery of this curative therapy to many patients with fatal hematological diseases. More than 1.5 million HCT were performed between 1957 and 2019, and activity is continuously increasing worldwide.
| Type: | Article |
|---|---|
| Title: | The role of registries in hematological disorders |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.beha.2024.101556 |
| Publisher version: | https://doi.org/10.1016/j.beha.2024.101556 |
| Language: | English |
| Additional information: | © 2024 The Authors. Published by Elsevier Ltd. under a Creative Commons license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Hematopoietic cell transplantation (HCT), Allogeneic HCT, Autologous HCT, Registries, Survey, Outcome registry, Leukemia |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10218311 |
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