O'Reilly, Helen;
Thiebaut, Flora I;
White, Sarah J;
(2013)
Is macrocephaly a neural marker of a local bias in autism?
Developmental Cognitive Neuroscience
, 6
pp. 149-154.
10.1016/j.dcn.2013.09.002.
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Abstract
Previous research has suggested that the local processing bias often reported in studies of Autism Spectrum Condition may only be typical of a subgroup of individuals with autism also presenting with macrocephaly. The current study examined a group of children with autism, with and without macrocephaly, on the Children's Embedded Figures Test (CEFT), a well-established measure of local processing bias. The results demonstrated that the children with autism and macrocephaly performed significantly better on the CEFT than children with autism without macrocephaly, indicative of a local bias. These results lend support to the proposal that both macrocephaly in autism and a local processing bias may arise from the same underlying neural processes and these characteristics represent an endophenotype in a subgroup of individuals with ASC worthy of further investigation.
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