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Endoscopic third ventriculostomy plus valveless catheter in the treatment of low-pressure hydrocephalus

Villalonga, Juan F; Saenz, Amparo; Pailler, José I; Castillo, Andrea L; Gomar Alba, Mario; Domenico, Solari; Campero, Alvaro; ... Cinalli, Guiseppe; + view all (2025) Endoscopic third ventriculostomy plus valveless catheter in the treatment of low-pressure hydrocephalus. Turkish Neurosurgery , 35 (6) pp. 830-838. 10.5137/1019-5149.jtn.47801-24.2. Green open access

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Abstract

AIM: To evaluate the outcomes in low-pressure hydrocephalus (LPH) following an endoscopic third ventriculostomy, and placement of a valveless ventriculoperitoneal or ventriculoatrial shunt catheter. MATERIAL and METHODS: This novel surgical technique was assessed in a prospective case series at a single center between December 2020 and December 2022. Patients were selected for the hybrid procedure based on the Pang?Altschuler diagnostic criteria for LPH. Those with normal or high-pressure hydrocephalus or less than six months of follow-up were excluded. All patients were evaluated clinically (Karnofsky performance status [KPS]) and radiologically (standardized set of images) in the preoperative and postoperative period, and their outcome was categorized as excellent, temporary improvement, or poor. RESULTS: This case series comprised 16 patients. The mean postoperative improvement in KPS was 56 points. All patients showed improved KPS. All follow-up scans showed radiological improvement. System dysfunction and the need for a shunt with a valve were detected in 18.75% of cases (n=3). The outcome was excellent in 81.25% of cases (n=13), and temporary improvement in 18.75% (n=3). CONCLUSION: The presented series demonstrated that the hybrid procedure effectively treats LPH and has minimal number of complications.

Type: Article
Title: Endoscopic third ventriculostomy plus valveless catheter in the treatment of low-pressure hydrocephalus
Open access status: An open access version is available from UCL Discovery
DOI: 10.5137/1019-5149.jtn.47801-24.2
Publisher version: https://doi.org/10.5137/1019-5149.jtn.47801-24.2
Language: English
Additional information: This is an Open Access article published under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/).
Keywords: Endoscopic, Hydrocephalus, Shunt, Low-pressure hydrocephalus, Valveless
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10218166
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