Haq, Zahra J;
Ahmed, Ahmed;
Abdelsalam, Alaa;
Chegini, Soudeh;
Kurzawinski, Tom R;
Morley, Simon;
Mcgurk, Mark;
(2024)
The development of patient-specific 3D anatomical models in minimally invasive parathyroidectomy.
Frontiers in Endocrinology
, 15
, Article 1514451. 10.3389/fendo.2024.1514451.
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Abstract
Background: Surgery is the preferred treatment for primary hyperparathyroidism. Minimally invasive parathyroidectomy is only feasible with accurate preoperative localisation. Virtual 3D anatomical models can be constructed from patient-specific CT scans using segmentation software. Methods: We aimed to create virtual 3D models from 4D-CT scans of parathyroid tumours using segmentation technology. We designed a small pilot study to assess the utility of 3D models within surgical practice. We assessed surgeon, trainee and patients’ opinion and satisfaction with the models. The NASA TLX survey was the primary data collection tool Results: Creation of novel 3D models was achieved, these featured a 360-degree axis of rotation and transparency mode to assist in surgical planning. Models were used intraoperatively with the HoloLens 2 headset to locate parathyroid tumours real time before surgery. Total mean workloads for surgery planning when averaged revealed a decrease workload (39.45 vs 27.45) points with adjunctive use of models (p=0.002). Mental demand showed the greatest decrease in mean workload out of all the 6 subscales tested for in the NASA TLX (210.3 vs 136.7) points. Patient satisfaction score was statistically significant for the difference before and after seeing the 3D model regarding anatomical location (p=≤0.001), Conclusion: In this work, we developed patient-specific virtual 3D anatomical models of parathyroid tumours for use in surgery using novel techniques, previously never applied to parathyroidectomy. Our initial success in model construction and subsequent opinion of surgeons, trainees and patients contributes to the developing body of literature in favour of virtual modelling for parathyroidectomy.
| Type: | Article |
|---|---|
| Title: | The development of patient-specific 3D anatomical models in minimally invasive parathyroidectomy |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fendo.2024.1514451 |
| Publisher version: | https://doi.org/10.3389/fendo.2024.1514451 |
| Language: | English |
| Additional information: | © 2024 Haq, Ahmed, Abdelsalam, Chegini, Kurzawinski, Morley, McGurk and Abdel-Aziz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Endocrinology & Metabolism, primary hyper parathyroidism, parathyroid - adenoma, parathyrodectomy, minimally invasive surgery, HoloLens 2, three-dimensional mode, PRIMARY HYPERPARATHYROIDISM |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10217361 |
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