Dalecka, Andrea;
Jeong, Ayoung;
Szabo, Daniel;
Tamasi, Balint;
Imboden, Medea;
Schaffner, Emmanuel;
Keidel, Dirk;
... Probst-Hensch, Nicole; + view all
(2025)
Air pollution, greenspace, and metabolic syndrome in older Czech and Swiss populations.
Environmental Epidemiology
, 9
(3)
, Article e393. 10.1097/EE9.0000000000000393.
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Abstract
Background: The prevalence of metabolic syndrome (MetS) has increased rapidly, with considerable variation between European countries. The study examined the relationship between air pollutants, greenspace, and MetS and its components in the Czech and Swiss populations. / / Methods: Cross-sectional data from the Czech Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE) (n = 4,931) and the Swiss cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA) (n = 4,422) cohorts included participants aged 44–73 years. MetS was defined as abdominal obesity plus two additional components (hypertension, diabetes, low high-density lipoprotein cholesterol, and elevated triglycerides). Annual mean concentrations of PM10, PM2.5, NO2, and greenspace (defined as the annual mean of normalized difference vegetation index within 500 m) were assigned to the individual residential level. We estimated odds ratios (OR) using multivariable logistic regressions with cluster-robust standard error, controlling for multiple confounders. / / Results: The prevalence of MetS was significantly higher in the Czech (51.1 per cent) compared with Swiss (35.8 per cent) population as were the concentration means of PM10 and PM2.5. In HAPIEE, a 5 μg/m3 increase in PM2.5 was associated with 14 per cent higher odds of MetS (OR = 1.14; 95 per cent confidence interval [CI] = 1.01, 1.28). In SAPALDIA, no evidence was found for the associations between air pollutants and MetS (for example OR = 1.01; 95 per cent CI = 0.90, 1.13 for PM2.5). No protective effects of normalized difference vegetation index on MetS were observed. Upon inspection of MetS components, PM2.5 and PM10 exposures were associated with higher odds of hypertension and elevated triglycerides in HAPIEE only, while PM2.5, PM10, and NO2 were associated with higher odds of diabetes in SAPALDIA only. / / Conclusion: Individuals with higher exposures to PM2.5 may be at higher risk of MetS. The differential associations with MetS components between the cohorts deserve further investigation.
| Type: | Article |
|---|---|
| Title: | Air pollution, greenspace, and metabolic syndrome in older Czech and Swiss populations |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/EE9.0000000000000393 |
| Publisher version: | https://doi.org/10.1097/EE9.0000000000000393 |
| Language: | English |
| Additional information: | © The Author(s), 2025. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Air pollution; Cross-sectional design; Greenspace; Metabolic syndrome; Particulate matter |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10217266 |
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