UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Pain mechanisms in the transgender individual: a review

Anger, JT; Case, LK; Baranowski, AP; Berger, A; Craft, RM; Damitz, LA; Gabriel, R; ... Yaksh, TL; + view all (2024) Pain mechanisms in the transgender individual: a review. Frontiers in Pain Research , 5 , Article 1241015. 10.3389/fpain.2024.1241015. Green open access

[thumbnail of Pain mechanisms in the transgender individual a review.pdf]
Preview
PDF
Pain mechanisms in the transgender individual a review.pdf - Accepted Version

Download (803kB) | Preview

Abstract

Specific Aim: Provide an overview of the literature addressing major areas pertinent to pain in transgender persons and to identify areas of primary relevance for future research. Methods: A team of scholars that have previously published on different areas of related research met periodically though zoom conferencing between April 2021 and February 2023 to discuss relevant literature with the goal of providing an overview on the incidence, phenotype, and mechanisms of pain in transgender patients. Review sections were written after gathering information from systematic literature searches of published or publicly available electronic literature to be compiled for publication as part of a topical series on gender and pain in the Frontiers in Pain Research. Results: While transgender individuals represent a significant and increasingly visible component of the population, many researchers and clinicians are not well informed about the diversity in gender identity, physiology, hormonal status, and gender-affirming medical procedures utilized by transgender and other gender diverse patients. Transgender and cisgender people present with many of the same medical concerns, but research and treatment of these medical needs must reflect an appreciation of how differences in sex, gender, gender-affirming medical procedures, and minoritized status impact pain. Conclusions: While significant advances have occurred in our appreciation of pain, the review indicates the need to support more targeted research on treatment and prevention of pain in transgender individuals. This is particularly relevant both for gender-affirming medical interventions and related medical care. Of particular importance is the need for large long-term follow-up studies to ascertain best practices for such procedures. A multi-disciplinary approach with personalized interventions is of particular importance to move forward.

Type: Article
Title: Pain mechanisms in the transgender individual: a review
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fpain.2024.1241015
Publisher version: https://doi.org/10.3389/fpain.2024.1241015
Language: English
Additional information: © 2024 Anger, Case, Baranowski, Berger, Craft, Damitz, Gabriel, Harrison, Kaptein, Lee, Murphy, Said, Smith, Thomas, Valdés Hernández, Trasvina, Wesselmann and Yaksh. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: gender affirming care, gender binary system, hormone replacement therapy (HRT), post operative pain, transgender (GLBT) issues
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10217072
Downloads since deposit
3Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item