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Impact of pre-existing subclinical depressive symptoms on the mental health of older adults during the COVID-19-related confinements: assessment of moderating factors including meditation training

Touron, Edelweiss; Gonneaud, Julie; Paly, Leo; Delarue, Marion; Hebert, Oriane; Mezenge, Florence; Fauvel, Severine; ... The Medit-Ageing Research Group, .; + view all (2025) Impact of pre-existing subclinical depressive symptoms on the mental health of older adults during the COVID-19-related confinements: assessment of moderating factors including meditation training. Scientific Reports volume , 15 , Article 15958. 10.1038/s41598-025-99059-9. Green open access

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Abstract

The COVID-19 pandemic significantly challenged mental health of populations worldwide. We aimed to assess changes in mental health of cognitively unimpaired (CU) older adults with pre-existing subclinical depressive symptoms during pandemic-related confinements, and the factors that could modulate these changes. CU older adults with (DepS, n = 53) and without (NoDepS, n = 47) pre-existing subclinical depressive symptoms (defined using the Geriatric Depression Scale at baseline) from the Age-Well randomized controlled trial (NCT02977819) were included – for whom data at baseline, post-intervention visits and during the two national confinements were available. The 18-month meditation or non-native language training intervention was completed before the pandemic. DepS, compared to NoDepS, had higher levels of depressive and anxiety symptoms at all assessments, including confinements. DepS had a greater increase in anxiety than NoDepS between the two confinements, and this increase was associated with greater ruminative brooding at baseline, but was not moderated by the meditation training intervention or by meditation practice during confinements. Pre-existing subclinical depressive symptoms in older adults contribute to mental health deterioration during confinements, with rumination being the main factor involved – stressing the need to treat these symptoms.

Type: Article
Title: Impact of pre-existing subclinical depressive symptoms on the mental health of older adults during the COVID-19-related confinements: assessment of moderating factors including meditation training
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41598-025-99059-9
Publisher version: https://doi.org/10.1038/s41598-025-99059-9
Language: English
Additional information: Copyright © The Author 2025. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.
Keywords: Depressive symptoms, Anxiety symptoms, Older adults, COVID-19 pandemic, Meditation,
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
URI: https://discovery.ucl.ac.uk/id/eprint/10216928
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