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Mediterranean diet score linked to cognitive functioning in Czech women: a cross-sectional population-based study

Hrezova, Eliska; Stefler, Denes; Capkova, Nadezda; Vaclova, Helena; Bobak, Martin; Pikhart, Hynek; (2025) Mediterranean diet score linked to cognitive functioning in Czech women: a cross-sectional population-based study. European Journal of Nutrition , 64 (5) , Article 237. 10.1007/s00394-025-03752-4. Green open access

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Abstract

Purpose: The evidence suggests that adherence to the Mediterranean diet (MD) may be beneficial in preventing cognitive decline. We aimed to explore this association in a Central European population. Methods: A total of 6,028 men and women from the Czech arm of the HAPIEE study were included in the analysis. Dietary data were collected using a food frequency questionnaire, and MD score (MDS) was calculated based on nine food groups. The MDS (range 0–17 points) was classified into three groups: low (0–7), medium (8–10), high (11–17). Cognitive function was measured using four tests assessing verbal memory and learning, verbal fluency, and attention, mental speed and concentration, and composite score, each of them converted to z-score. The associations between MDS and cognitive function were analyzed using multivariate linear regression in men and women. Results: There were no significant associations in men. By contrast, women with a dietary score of 8–10 points (B = 0.05, 95% CI: -0.002; 0.097), and those with a score of 11–17 points (B = 0.08, 95% CI: 0.016; 0.140) had a higher composite cognitive score than women in lowest adherence group. Regarding specific domains, women in the highest adherence group had significantly better immediate verbal memory (B = 0.12, 95% CI: 0.031; 0.205) and delayed recall (B = 0.12, 95% CI: 0.027; 0.212), respectively, than those in the lowest adherence group. Conclusion: Higher adherence to the MDS was associated with better cognitive functioning in verbal memory and composite cognitive score in Czech women. The results suggest that the Mediterranean diet may help to improve cognitive functioning.

Type: Article
Title: Mediterranean diet score linked to cognitive functioning in Czech women: a cross-sectional population-based study
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00394-025-03752-4
Publisher version: https://doi.org/10.1007/s00394-025-03752-4
Language: English
Additional information: Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Science & Technology, Life Sciences & Biomedicine, Nutrition & Dietetics, Cognition, Cognitive decline, Mediterranean, Diet, Dietary habits, Aging, CARDIOVASCULAR-DISEASE, RISK, DEMENTIA, DECLINE, IMPAIRMENT, PATTERNS, HABITS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10216896
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