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Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA)

John, Amber; Desai, Roopal; Eshetu, Aphrodite; Willroth, Emily; Marchant, Natalie; Woodward-Carlton, Barbara; Cadar, Dorina; ... Stott, Joshua; + view all (2025) Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA). Aging & Mental Health , 29 (10) pp. 1807-1813. 10.1080/13607863.2025.2468408. Green open access

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Abstract

Objectives: The aim of this study was to test the bidirectional relationship between wellbeing and memory in a large, nationally representative sample of people aged 50+. Method: Data were used from the English Longitudinal Study of Ageing (ELSA), a longitudinal cohort comprising 12,099 people aged 50+, excluding people with dementia at baseline. Repeated measures of wellbeing (CASP-19) and episodic memory (immediate and delayed recall of a word list) were available 9-times over a 16-year period. Cross-lagged models were fitted to test bidirectional relationships between wellbeing and memory. Results: Higher wellbeing was associated with higher subsequent immediate and delayed memory scores at all time points, though effect sizes were small (standardised betas ranging from 0.04–0.07). There was not evidence that higher memory scores were associated with subsequent wellbeing. Conclusion: Higher levels of wellbeing are associated with better memory function over 16 years. The study does not provide evidence that the association operates in the opposite direction. The lack of evidence for a relationship between memory and subsequent wellbeing may suggest that associations in this direction only emerge after development of clinically-relevant cognitive impairment. Better wellbeing may be a protective factor in retaining memory function from middle to later adulthood.

Type: Article
Title: Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA)
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/13607863.2025.2468408
Publisher version: https://doi.org/10.1080/13607863.2025.2468408
Language: English
Additional information: © 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
Keywords: Wellbeing; memory; longitudinal; ageing; cohort study
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine > MRC Unit for Lifelong Hlth and Ageing
URI: https://discovery.ucl.ac.uk/id/eprint/10216783
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