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Prostate cancer diagnosis, classification and treatment overview

Shaw, Greg; Almeida-Magana, Ricardo; (2025) Prostate cancer diagnosis, classification and treatment overview. Surgery (Oxford) , 43 (10) pp. 648-656. 10.1016/j.mpsur.2025.07.016.

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Abstract

Prostate cancer is the most frequently diagnosed malignancy in adult males. It has a multifactorial aetiology and highly variable clinical course which ranges from an indolent disease, suitable for active surveillance, to an aggressive disease requiring multimodal treatment. Early detection is guided by prostate-specific antigen (PSA) testing, imaging, and biopsy, while management of localized disease is based on risk stratification. Advances in systemic therapies have significantly improved survival and quality of life in advanced stages. This article provides an up-to-date overview of the evolving landscape of prostate cancer diagnosis and treatment.

Type: Article
Title: Prostate cancer diagnosis, classification and treatment overview
DOI: 10.1016/j.mpsur.2025.07.016
Publisher version: https://doi.org/10.1016/j.mpsur.2025.07.016
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Male health; prostate cancer; PSA; urology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10216763
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