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ACR Appropriateness Criteria® Assessment of Cardiac Function and Baseline Cardiac Risk Stratification in Oncology Patients

Meyersohn, NM; Parakh, A; Ghoshhajra, BB; Agarwal, PP; Bourque, JM; Chamarthy, MRK; De Cecco, CN; ... Koweek, LM; + view all (2025) ACR Appropriateness Criteria® Assessment of Cardiac Function and Baseline Cardiac Risk Stratification in Oncology Patients. Journal of the American College of Radiology , 22 (5) S67-S78. 10.1016/j.jacr.2025.02.038.

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Abstract

Cardiac risk stratification is clinically useful prior to initiation of oncologic therapy in asymptomatic patients in order to guide treatment decisions and allow for initiation of cardioprotective therapy or modification of treatment regimens. Once oncology treatment is underway, patients may develop cardiac symptoms. In this setting, imaging can be used for assessment of ventricular and valvular function, myocardial characterization, pericardial effusion or constriction, as well as to evaluate for ischemia as a cause of symptoms. Results can help guide treatment choices and shared decision-making regarding modification or cessation of treatments with associated cardiotoxicity. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation.

Type: Article
Title: ACR Appropriateness Criteria® Assessment of Cardiac Function and Baseline Cardiac Risk Stratification in Oncology Patients
Location: United States
DOI: 10.1016/j.jacr.2025.02.038
Publisher version: https://doi.org/10.1016/j.jacr.2025.02.038
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: AUC, Appropriateness Criteria, appropriate use criteria, cardiac risk stratification, cardio-oncology, cardiotoxicity, oncologic therapy, Humans, Risk Assessment, Neoplasms, United States, Evidence-Based Medicine, Societies, Medical, Heart Diseases, Cardiotoxicity, Antineoplastic Agents
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10215526
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