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What can flies teach us about brain diseases?

Wilson, Abigail D; Lowe, Simon A; Jepson, James EC; Aughey, Gabriel N; (2024) What can flies teach us about brain diseases? Frontiers for Young Minds , 12 , Article 1281006. 10.3389/frym.2024.1281006. Green open access

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Abstract

Diseases that affect the brain are one of the leading causes of disability worldwide. Many doctors and scientists are trying to work out how these diseases arise and how they can be treated. Unfortunately, the brain is an extremely complicated organ, so this goal is very challenging. One way of simplifying this challenge is to look at simpler brains. For example, a human brain has about 100,000 times more brain cells than a fruit fly brain, but it works in a similar way. Although a fruit fly may seem very different from a human, we still have a lot in common. For example, we both have brains that control how we move our bodies. Scientists are using fruit fly brains to study a wide range of brain diseases that affect human patients. Fly brains can be used to understand how a disease happens, and they can even be used to test drugs to discover new medicines. This article gives an overview of how scientists are using flies to help understand and treat brain disorders.

Type: Article
Title: What can flies teach us about brain diseases?
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/frym.2024.1281006
Publisher version: https://doi.org/10.3389/frym.2024.1281006
Language: English
Additional information: Copyright © 2024 Wilson, Lowe, Jepson and Aughey. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
URI: https://discovery.ucl.ac.uk/id/eprint/10215366
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