Mehta, Dipal;
Gabriel, Maria;
Adu-Poku, Nathan;
Kanellias, Nikolaos;
Papanikolaou, Xenofon;
Sive, Jonathan;
Rabin, Neil;
... Kyriakou, Charalampia; + view all
(2025)
The Role of Radiotherapy for Patients With Multiple Myeloma in the Modern Era: A Real World Single-Centre Experience.
eJHaem
, 6
(5)
, Article e70141. 10.1002/jha2.70141.
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Abstract
Background: Radiotherapy (RT) is a well-established treatment modality in multiple myeloma (MM), particularly for skeletal-related events. However, its role is likely evolving with the introduction of modern systemic treatments. // Methods: We conducted a retrospective analysis of a large, single-centre MM cohort treated with contemporary protocols to describe current patterns of RT use. // Results: RT continues to offer clinical benefit, with shifting patterns of use observed compared to historical cohorts. // Conclusion: RT remains relevant in the modern MM landscape and may hold increasing value in later treatment stages. We postulate a future role as bridging therapy prior to CAR-T/bispecific antibody treatment. // Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.
| Type: | Article |
|---|---|
| Title: | The Role of Radiotherapy for Patients With Multiple Myeloma in the Modern Era: A Real World Single-Centre Experience |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/jha2.70141 |
| Publisher version: | https://doi.org/10.1002/jha2.70141 |
| Language: | English |
| Additional information: | Copyright © 2025 The Author(s). eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, https://creativecommons.org/licenses/by/4.0/, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Myeloma; myeloma treatment; radiotherapy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10215166 |
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