Mitchell, Hannah K;
Pujol, Ferran Espuny;
Franklin, Rodney C;
Ambler, Gareth;
Stickley, John;
Taylor, Julie A;
Van Doorn, Carin;
... Brown, Katherine L; + view all
(2025)
Risk models for monitoring post-operative complication rates after pediatric cardiac surgery.
European Journal of Cardio-Thoracic Surgery
, Article ezaf317. 10.1093/ejcts/ezaf317.
(In press).
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Abstract
OBJECTIVES: As post-operative mortality for paediatric cardiac surgery is very low, we aimed to develop methods for monitoring of post-operative complication rates, given their impact upon children’s health and wellbeing. // METHODS: We used national registry data to develop and evaluate a suite of risk adjustment models for the outcomes of 6 defined post-operative complications, designed for use in complication monitoring for quality assurance. // RESULTS: There were 23,423 30-day post-operative episodes in children under the age of 18-years undergoing cardiac surgery between 2015–2021 in England and Wales, with 361 (1.5%) deaths <30-days. 257 (1.9%) of 13,556 post-operative episodes in infants (<1 year) involved necrotising enterocolitis; 158 (1.3%) of 12,408 post-operative episodes between 2018 and 2021 involved prolonged pleural effusion; and amongst the full sample of post-operative episodes there were 526 (2.2%) acute neurological events, 446 (1.9%) extracorporeal life supports, 740 (3.6%) renal replacement therapies and 1,006 (4.3%) unplanned reinterventions within 30-days of surgery. The risk adjustment models were developed using clinical factors first defined for mortality monitoring. The models for prolonged pleural effusion, extracorporeal life support and renal replacement performed very well with area under the curve (AUC) statistics >0.85. The performance of the models for necrotising enterocolitis, acute neurological event and unplanned reintervention were less good (AUC statistics 0.74–0.79). // CONCLUSIONS: Although complications are more complex outcome measures than mortality, national registry data can be used to capture them and to evaluate methods for risk adjustment of these outcomes. These methods may enable future risk-adjusted monitoring of complication metrics for quality assurance.
| Type: | Article |
|---|---|
| Title: | Risk models for monitoring post-operative complication rates after pediatric cardiac surgery |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/ejcts/ezaf317 |
| Publisher version: | https://doi.org/10.1093/ejcts/ezaf317 |
| Language: | English |
| Additional information: | Copyright © The Author(s) 2025. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Cardiac surgery, outcomes, care quality, complications |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics > Clinical Operational Research Unit |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10214694 |
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