Greenslade, Molly;
(2025)
An fMRI study investigating the relationship between trauma memory decontextualization in PTSD with concurrent psychosis.
Doctoral thesis (D.Clin.Psy), UCL (University College London).
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Abstract
AIMS: The primary aim of this systematic narrative review is to further understand the relationship and prevalence between trauma and premenstrual disorders (including both Premenstrual Syndrome and Premenstrual Dysphoric Disorder). Secondary aims of the review were to explore differences across trauma type and their association to PMDs and to identify mediating factors for this relationship. METHODS: Two bibliographic databases (PsycINFO and PubMed) were used to search for empirical literature related to the research question. Inclusion criteria were expanded to investigate any type of traumatic experiences, and any premenstrual-related mood disorders were included. A narrative approach was used, and no meta-analysis was performed. RESULTS: Twenty-seven studies were identified for inclusion and subjected to a quality appraisal. The majority of the research (26/27) found a significant association with traumatic experiences and PMD symptomology. Key themes were synthesised from the results of the 27 papers and discussed in detail: Prevalence of trauma in PMS/PMDD populations, types of traumas and their associations with PMDs, Complex PTSD and PTSD, and mediators of the relationship between trauma and PMD. DISCUSSION: This review highlighted the significant association between trauma and PMDD and offered further understanding of the potential mechanisms and mediators influencing this relationship. Furthermore, this review shines a light on the lack of guidance and diagnostic frameworks within this population. It stresses the need for trauma-informed approaches and further research into the underlying neurobiological pathways to improve treatment.
| Type: | Thesis (Doctoral) |
|---|---|
| Qualification: | D.Clin.Psy |
| Title: | An fMRI study investigating the relationship between trauma memory decontextualization in PTSD with concurrent psychosis |
| Open access status: | An open access version is available from UCL Discovery |
| Language: | English |
| Additional information: | Copyright © The Author 2025. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10214608 |
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