Grima, Lara;
Davenport, Sally;
Parry-Jones, Adrian R;
Vail, Andy;
Hammerbeck, Ulrike;
(2025)
Comparing upper limb motor recovery in subacute ischaemic stroke and intracerebral haemorrhage: A Systematic Review.
Health Open Research
, 5
, Article 33. 10.12688/healthopenres.13450.2.
Preview |
Text
Lara_Grima_UL_SR.pdf - Published Version Download (1MB) | Preview |
Abstract
BACKGROUND: The pathophysiology and medical management between ischaemic stroke and intracerebral haemorrhage differ as do their functional independence and mortality outcomes. This paper aims to establish whether their respective upper limb motor impairment and recovery differ. This information could inform discussions with patients about their recovery prognosis as well as identify appropriate rehabilitation settings. METHODS: A PROSPERO registered systematic search of three databases (MEDLINE, CINAHL, Embase) identified studies that measured upper limb motor function (Fugl-Meyer assessment scale for upper extremity) in participants with first stroke (ischaemic stroke or intracerebral haemorrhage) within 31 days post-stroke and at least one follow-up assessment. Risk of bias was assessed using the Critical Appraisal Skills Programme. RESULTS: The search identified 1108 studies of which three met inclusion criteria, with a total of 258 participants (200 ischaemic stroke, 58 intracerebral haemorrhage). All studies had low to moderate risk of bias. At baseline, participants with intracerebral haemorrhage had greater upper limb motor impairment on the Fugl-Meyer assessment scale, but at six months post-stroke, the stroke subtypes reached similar upper limb motor function. Improvements were greatest early after stroke. CONCLUSIONS: Despite greater severity at baseline, intracerebral haemorrhage survivors appeared to reach the same level of arm function at six months post stroke. However, these findings need to be interpreted with caution due to limited studies and small number of participants included in this review and warrant further research. PROSPERO REGISTRATION: CRD42020159110 (19/02/2020).
| Type: | Article |
|---|---|
| Title: | Comparing upper limb motor recovery in subacute ischaemic stroke and intracerebral haemorrhage: A Systematic Review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.12688/healthopenres.13450.2 |
| Publisher version: | https://doi.org/10.12688/healthopenres.13450.2 |
| Language: | English |
| Additional information: | © 2025 Grima L et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10214375 |
Archive Staff Only
 |
View Item |
