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Architecture for the Holobiont Designing Probiotic Interventions

Beckett, Richard; (2023) Architecture for the Holobiont Designing Probiotic Interventions. In: Crawford, A and Diniz, N and Beckett, R and Vanucchi, M and Swackhamer, M, (eds.) ACADIA 2023: Habits of the Anthropocene: Scarcity and Abundance in a Post-Material Economy [Volume 2: Proceedings of the 43rd Annual Conference for the Association for Computer Aided Design in Architecture. (pp. pp. 220-229). Association for Computer Aided Design in Architecture Green open access

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Abstract

This paper details a biodigital, probiotic design approach to creating biologically active material systems for buildings. These living materials are beneficial for the health of the human holobiont body through their impact on the human microbiome and potential to shape immunoregulatory health. I frame the research within the context of bio-inte- grated design in architecture and engineered living materials (ELM’s), but with novel focus on microbiome health in urban environments. I introduce the discipline of microbiome science and its associated metagenomic technologies that show how it may be possible for bio-integrated design approaches to reshape the indoor microbiome of buildings. We propose a computational methodology towards designing and fabricating hybrid living building components that serve as both a niche and a source of symbiotically important microbes for buildings. A biodigital approach is presented, driven by current knowledge of the indoor microbiome and indoor environmental conditions that promote beneficial microbial transmissions via mechanisms of touch, ingestion, and respiration. This is presented through an experimental project which develops a human-machine-microbe fabrication process to create a living prototype which is then explored and assessed through an intervention study using a 16S metagenomic analysis.

Type: Proceedings paper
Title: Architecture for the Holobiont Designing Probiotic Interventions
Event: 43rd Annual Conference for the Association for Computer Aided Design in Architecture (ACADIA)
Location: Denver, CO, USA
Dates: 21st-28th October 2023
ISBN-13: 979-8-9860805-9-8
Open access status: An open access version is available from UCL Discovery
Publisher version: https://papers.cumincad.org/cgi-bin/works/paper/ac...
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment > The Bartlett School of Architecture
URI: https://discovery.ucl.ac.uk/id/eprint/10214323
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