McQuillin, A; Ophoff, RA; (2025) Genomics of Bipolar Disorder: What the Clinician Needs to Know. Psychiatric Clinics of North America , 48 (2) pp. 331-341. 10.1016/j.psc.2025.01.009.

Text McQuillin_Bipolar Book Chapter Draft_24April2024.pdf Access restricted to UCL open access staff until 18 March 2026. Download (325kB)

Abstract

Bipolar disorder (BD) affects approximately 2% of the global population, characterized by alternating episodes of mania or hypomania, and depression. It comprises two main types: bipolar I disorder, marked by severe manic episodes, and bipolar II disorder, defined by milder hypomanic episodes. Individuals often experience rapid cycling and significant comorbidities, leading to decreased productivity and increased mortality rates. Early diagnosis and intervention are crucial for better outcomes. Both genetic and environmental factors contribute to BD's etiology, with genetic research promising improved diagnosis, novel therapeutic targets, and societal understanding that may help destigmatize the disorder.

Download activity - last month

Export as JSONXMLCSV

Download activity - last 12 months

Export as JSONCSVXML

Downloads by country - last 12 months

Export as JSONXMLCSV

Archive Staff Only

View Item