Sideli, L;
Aas, M;
Alameda, L;
Trotta, G;
La Barbera, D;
La Cascia, C;
Ferraro, L;
... Fisher, HL; + view all
(2025)
Interplay Between Childhood Maltreatment, Subclinical Post-Traumatic Stress Symptoms, and IQ: Findings From the EU-GEI Multicentre Case–Control Study.
Early Intervention in Psychiatry
, 19
(8)
, Article e70079. 10.1111/eip.70079.
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Abstract
Introduction: Evidence suggests that childhood maltreatment affects cognitive performance in both patients with psychosis and community controls. However, the interplay between childhood maltreatment, post-traumatic stress symptoms (PTSS), and intelligence has not been investigated. This study investigated the relationship between childhood maltreatment, subclinical PTSS, and intelligence among patients with first-episode psychosis (FEP) and community controls. / Methods: Patients with FEP (N = 602) and controls (N = 853) from the EU-GEI study were assessed for childhood maltreatment, PTSS, and intelligence quotient (IQ). / Results: PTSS were associated with lower IQ among community controls but not among patients with FEP. In the FEP group, an interaction (p = 0.044) between PTSS and childhood maltreatment on IQ was found, such that the association between PTSS and lower IQ was only present among those exposed to childhood maltreatment. No interaction was evident in controls (p = 0.826). / Conclusions: The findings suggest the relevance of cognitive rehabilitation for FEP patients with childhood maltreatment and PTSS.
| Type: | Article |
|---|---|
| Title: | Interplay Between Childhood Maltreatment, Subclinical Post-Traumatic Stress Symptoms, and IQ: Findings From the EU-GEI Multicentre Case–Control Study |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/eip.70079 |
| Publisher version: | https://doi.org/10.1111/eip.70079 |
| Language: | English |
| Additional information: | Copyright © 2025 The Author(s). Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | childhood maltreatment, first episode, intelligence, post-traumatic stress, psychosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Epidemiology and Applied Clinical Research |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10213086 |
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