Yang, Ren;
Ma, Xiaohan;
Xuan, Mingcheng;
Ma, Yingqi;
Ding, Jiexian;
Chau, David YS;
Knowles, Jonathan C;
... Poma, Alessandro; + view all
(2025)
Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications.
ChemistryOpen
, Article 2500127. 10.1002/open.202500127.
Preview |
PDF
ChemistryOpen - 2025 - Yang - Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic.pdf - Published Version Download (13MB) | Preview |
Abstract
This review explores the application of molecularly imprinted polymers (MIPs) in detecting bone turnover biomarkers and advancing osteogenic treatment strategies. MIPs, designed to mimic biological recognition sites, offer innovative solutions for precise molecular recognition in bone health management. Chemical methodologies for MIPs synthesis and their integration into diagnostic systems for detecting bone resorption markers are highlighted. Furthermore, MIP-driven therapeutic advancements, including controlled drug release, cell imprinting for osteogenic differentiation, and functional scaffolds for tissue regeneration, are emphasized. This review underscores MIPs' potential to revolutionize bone disease management and calls for further exploration into chemical designs to optimize their clinical and practical applications.
| Type: | Article |
|---|---|
| Title: | Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/open.202500127 |
| Publisher version: | https://doi.org/10.1002/open.202500127 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, bone biomarkers, controlled drug release, molecularly imprinted polymers, osteogenic treatment, tissue engineering, SOLID-PHASE SYNTHESIS, PRECIPITATION POLYMERIZATION, EXTRACELLULAR-MATRIX, SELECTIVE DETECTION, BIOACTIVE GLASS, CROSS-LINKING, MIP, SCAFFOLDS, NANOPARTICLES, COMPOSITE |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Biomaterials and Tissue Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10211932 |
Archive Staff Only
 |
View Item |
