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Research recommendations for assessing potential harm from universal school-based mental health interventions

Foulkes, Lucy; Andrews, Jack L; Reardon, Tessa; Stringaris, Argyris; (2024) Research recommendations for assessing potential harm from universal school-based mental health interventions. Nature Mental Health , 2 (3) pp. 270-277. 10.1038/s44220-024-00208-2. Green open access

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Abstract

There is growing evidence that universal school-based mental health interventions can lead to negative outcomes in young people. This is a critical ethical issue, especially when young people cannot easily opt out of interventions run during school hours. So far, however, there is no guidance available about potential harms for researchers designing and running these interventions. In this Perspective, we set out five research recommendations: (1) acknowledge the possibility of potential harms; (2) identify types of potential harms; (3) measure and report potential harms in all outputs; (4) consider adverse events (for example, a suicide attempt); and (5) consider participant dropout and disengagement. Using simulated data, we demonstrate that even if trials show small negative effects, this could lead to considerable harm if interventions are scaled up across the population. Furthering research in this area will help ensure the field delivers interventions that are most effective and least harmful for everyone.

Type: Article
Title: Research recommendations for assessing potential harm from universal school-based mental health interventions
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s44220-024-00208-2
Publisher version: https://doi.org/10.1038/s44220-024-00208-2
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: ANXIETY, CHILD, DEPRESSION, DROPOUT, Life Sciences & Biomedicine, Psychiatry, RANDOMIZED-TRIALS, Science & Technology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10211288
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