Harper, Danielle J;
Kim, Yongjoo;
Gómez-Ramírez, Alejandra;
Vakoc, Benjamin J;
(2023)
Needle guidance with Doppler-tracked polarization-sensitive optical coherence tomography.
Journal of Biomedical Optics
, 28
(10)
, Article 102910. 10.1117/1.JBO.28.10.102910.
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Abstract
SIGNIFICANCE: Optical coherence tomography (OCT) can be integrated into needle probes to provide real-time navigational guidance. However, unscanned implementations, which are the simplest to build, often struggle to discriminate the relevant tissues. AIM: We explore the use of polarization-sensitive (PS) methods as a means to enhance signal interpretability within unscanned coherence tomography probes. APPROACH: Broadband light from a laser centered at 1310 nm was sent through a fiber that was embedded into a needle. The polarization signal from OCT fringes was combined with Doppler-based tracking to create visualizations of the birefringence properties of the tissue. Experiments were performed in (i) well-understood structured tissues (salmon and shrimp) and (ii) ex vivo porcine spine. The porcine experiments were selected to illustrate an epidural guidance use case. RESULTS: In the porcine spine, unscanned and Doppler-tracked PS OCT imaging data successfully identified the skin, subcutaneous tissue, ligament, and epidural spaces during needle insertion. CONCLUSIONS: PS imaging within a needle probe improves signal interpretability relative to structural OCT methods and may advance the clinical utility of unscanned OCT needle probes in a variety of applications.
| Type: | Article |
|---|---|
| Title: | Needle guidance with Doppler-tracked polarization-sensitive optical coherence tomography |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/1.JBO.28.10.102910 |
| Publisher version: | https://doi.org/10.1117/1.JBO.28.10.102910 |
| Language: | English |
| Additional information: | © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.JBO.28.10.102910] |
| Keywords: | birefringence, imaging coherence, lasers in medicine, polarization, Animals, Swine, Tomography, Optical Coherence, Skin, Light, Refraction, Ocular, Birefringence |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10210937 |
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