Vaiana, Alexandra;
Behr, Jonathan;
Birol, Ryan;
Blauwendraat, Cornelis;
Casey, Bradford;
Chowdhury, Kushan;
Citron, Martin;
... Skibinski, Gaia; + view all
(2025)
A community-led initiative to de-risk and advance Parkinson’s disease therapeutic targets.
npj Parkinson's Disease
, 11
, Article 179. 10.1038/s41531-025-01039-3.
Preview |
Text
s41531-025-01039-3.pdf - Published Version Download (2MB) | Preview |
Abstract
Identifying effective therapeutic targets for Parkinson’s disease (PD) is challenging, with no current disease-modifying therapies available. To address this, The Michael J. Fox Foundation for Parkinson’s Research launched the Targets to Therapies (T2T) initiative, uniting experts to prioritize and validate promising targets. T2T aims to develop validation strategies, create comprehensive target data profiles, and build tools to support drug development, ultimately accelerating the discovery of new therapies for PD patients.
| Type: | Article |
|---|---|
| Title: | A community-led initiative to de-risk and advance Parkinson’s disease therapeutic targets |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41531-025-01039-3 |
| Publisher version: | https://doi.org/10.1038/s41531-025-01039-3 |
| Language: | English |
| Additional information: | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10210441 |
Archive Staff Only
 |
View Item |
