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In danger: HIV vaccine research and development in Europe

Tatoud, Roger; Levy, Yves; Le Grand, Roger; Alcami, Jose; Barbareschi, Giorgio; Brander, Christian; Cara, Andrea; ... Lelievre, Jean Daniel; + view all (2025) In danger: HIV vaccine research and development in Europe. PLOS Global Public Health , 5 (4) , Article e0004364. 10.1371/journal.pgph.0004364. Green open access

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Abstract

Highly effective antiretroviral-based HIV prevention plays an important role in ending the global HIV/AIDS epidemic. However, the sustainable control of the epidemic is hampered by unequal access to prevention options, including HIV testing, alongside with drug resistance and ongoing barriers to accessing sustainable HIV treatment. Therefore, an HIV vaccine, combined with effective prevention and treatment, remains an absolute necessity to control the epidemic. Yet, the recent discontinuation of four major vaccine efficacy studies is raising concerns about the future of HIV vaccine research and development globally, and particularly in the European region where funding for vaccine research and development has shrinked. This viewpoint emphasises that supporting HIV vaccine research and development at the European level remains crucial: it is not only necessary to control the epidemic, but it promotes innovation, strengthens health security, epidemic preparedness, and health sovereignty while contributing to the economies of European nations.

Type: Article
Title: In danger: HIV vaccine research and development in Europe
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pgph.0004364
Publisher version: https://doi.org/10.1371/journal.pgph.0004364
Language: English
Additional information: Copyright: © 2025 Tatoud et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: Science & Technology, Life Sciences & Biomedicine, Public, Environmental & Occupational Health
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10209962
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