Christodoulou, Demetra;
Reeves, Suzanne;
Carvalhoa, Naashoma;
Stellman, Judith;
Gould, Rebecca;
(2026)
A systematic review of third-wave therapies to reduce distress and improve wellbeing and quality of life in people with Parkinson's disease.
Clinical Gerontologist
10.1080/07317115.2025.2511957.
(In press).
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Abstract
Objectives: This systematic review assessed use of third-wave psychotherapies in reducing psychological distress and improving psychological well-being and quality of life in people with Parkinson’s disease and critically evaluated intervention adaptations. Methods: A literature search, conducted across five databases identified randomized controlled trials (RCTs) evaluating third-wave psychotherapies for individuals with Parkinson’s disease. Results: Ten RCTs were identified of which nine evaluated mindfulness-based interventions, and one acceptance and commitment therapy. Methodological quality ranged from moderate to high, but sample sizes were small, and only one study was adequately powered. Five reported on Parkinson’s specific adaptations. The trial with the largest sample size reported a significant effect of Mindfulness Yoga on depression and anxiety, psychological well-being and quality of life. Other findings were mixed across all outcomes. Conclusions: There was evidence of an effect of Mindfulness Yoga on our pre-defined outcomes. Pilot and feasibility trials showed that mindfulness-based interventions were well received and provided feedback on adaptations. There was a lack of data to draw conclusions regarding nonmindfulness-based therapies. Clinical implications: Larger trials of mindfulness-based interventions are required to establish the clinical meaningfulness of treatment effects. Further research is needed to adapt and explore on non-mindfulness-based interventions such as acceptance and commitment therapy.
| Type: | Article |
|---|---|
| Title: | A systematic review of third-wave therapies to reduce distress and improve wellbeing and quality of life in people with Parkinson's disease |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/07317115.2025.2511957 |
| Publisher version: | https://doi.org/10.1080/07317115.2025.2511957 |
| Language: | English |
| Additional information: | © 2025 The Author(s). Published with license by Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-ncnd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. |
| Keywords: | Parkinson’s disease; psychological distress; psychological well-being quality of life; systematic review; third-wave psychotherapies |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10208909 |
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