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Clinical Implementation of Artificial Intelligence in Gastroenterology: Current Landscape, Regulatory Challenges, and Ethical Issues

El-Sayed, Ahmed; Lovat, Laurence B; Ahmad, Omer F; (2025) Clinical Implementation of Artificial Intelligence in Gastroenterology: Current Landscape, Regulatory Challenges, and Ethical Issues. Gastroenterology 10.1053/j.gastro.2025.01.254. (In press). Green open access

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Abstract

Artificial intelligence (AI) is set to rapidly transform gastroenterology, particularly in the field of endoscopy, where algorithms have demonstrated efficacy in addressing human operator variability. However, implementing AI in clinical practice presents significant challenges. The regulatory landscape for AI as a medical device continues to evolve with areas of uncertainty. More robust studies generating real-world evidence are required to ultimately demonstrate impacts on patient outcomes. Cost-effectiveness data and reimbursement models will be pivotal for widespread adoption. Novel challenges are posed by emerging technologies, such as generative AI. Ethical and medicolegal concerns exist relating to data governance, patient harm, liability, and bias. This review provides an overview for clinical implementation of AI in gastroenterology and offers potential solutions to current barriers.

Type: Article
Title: Clinical Implementation of Artificial Intelligence in Gastroenterology: Current Landscape, Regulatory Challenges, and Ethical Issues
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1053/j.gastro.2025.01.254
Publisher version: https://doi.org/10.1053/j.gastro.2025.01.254
Language: English
Additional information: © 2025 The Author(s). Published by Elsevier Inc. on behalf of the AGA Institute under the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/).
Keywords: Artificial Intelligence, Endoscopy, Gastroenterology, Implementation, Regulation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10208089
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